Systemic inflammation and immune response after laparotomy vs laparoscopy in patients with acute cholecystitis, complicated by peritonitis

Figure 5 Chronological change in the serum level of interleukin-1β and interleukin-6β after surgery. A: The chronological change in the serum level of interleukin-1β (IL-1β) after surgery. Regarding IL-1β values, the difference between baseline values and post-operative values were significant in both groups (using the Friedman test, ^aP < 0.05); B: The chronological change in the serum level of interleukin-6β after surgery. Regarding IL-6β values, the difference between baseline values and post-operative values were significant in both groups (using the Friedman test, ^aP < 0.05). LC: Laparoscopic cholecystectomy; OC: Open cholecystectomy.