Systemic inflammation and immune response after laparotomy vs laparoscopy in patients with acute cholecystitis, complicated by peritonitis

Table 2 Demographics and clinical characteristics of four patients who developed intra-abdominal abscess

Patients (n)	1	2	3	4
Age (yr)	46	71	62	48
ASA	I	III	II	II
WBC count1 (mL)	14.800	13.600	19.200	13.200
HLA-DR2	7%	4%	7.80%	4.10%
PMN-elastase3 (mg/L)	69.6	70.2	70.6	78.2
IL-14 (pg/mL)	42.6	48.1	36.9	41.3
IL-65 (pg/mL)	415.16	381.8	402.25	408.4
Blood cultures6	Positive	Positive	Negative	Positive
Systemic endotoxin7 (pg/mL)	18.4	19.6	18.2	19.2

¹WBC count normalized 7-12 d after surgery;

²HLA-DR normalized 8-10 d after surgery;

³PMN-elastase normalized 8-12 d after surgery;

⁴ IL-1 normalized 10-13 d after surgery;

⁵IL-6 normalized 11-13 d after surgery;

⁶Blood cultures normalized 3-4 d after surgery;

⁷Systemic endotoxin concentration normalized 5-6 d after surgery. ASA: American society of anesthesiologists; WBC: White blood cells; HLA-DR: Human leukocyte antigen-DR; PMN: Polymorphonuclear; IL-1: Interleukin-1.