Extensive multiarterial resection attending total duodenopancreatectomy and adrenalectomy for MEN-1-associated neuroendocrine carcinomas

Figure 8 Histopathogical features and immunohistochemical characteristics of pancreatic head neuroendocrine carcinoma. A: Predominantly solid type of tumor cell growth, HE stain, × 75; B: Comedo-type structure with necrotic focus, HE stain, × 150; C: Strong synaptophysin expression in tumor cells, × 200; D: Strong diffuse chromogranin A expression in tumor cells, × 200; E: Cytokeratin 19 expression in tumor cells, × 200; F: A Ki-67 proliferative index of 40% by immunohistochemistry, × 200.