Current state of surgical treatment of liver metastases from colorectal cancer

Table 3 Two stage hepatectomy in patients with colorectal liver metastases

Author	Yr	Patients (n)		Survival
		Planned	Feasible
Adam et al[105]	2000	16	13a	35% 3-year OS
Jaeck et al[106]	2004	33	25	54.4% 3-year OS
Togo et al[108]	2005	11	11	45 % 3-year OS
Wicherts et al[109]	2008	59	41	42% 5-year OS
				13% 5-year DFS
Tsai et al[107]	2010	45	35	58% 3-year OS
Karoui et al[110]	2010	33	25b	48% 5-year OS
				22% 5-year DFS

OS: Overall survival; DFS: Disease-free survival.

^aPatients are included in Wicherts et al[109];

^bBilobar synchronous metastases-combined colorectal resection and clearance of one liver lobe as the first stage procedure.