Current state of surgical treatment of liver metastases from colorectal cancer

Table 1 Simultaneous vs staged resection of colorectal cancer and synchronous colorectal liver metastases

Author	Patients (n)		Morbidity		Comment
	Sta	Sim	Sta	Sim
Martin et al[73]	160	70	55%	56%	Major hepatectomy rate: Sta 32 % vs Sim 33 %
Slupski et al[74]	61	28	13%	14%	Major hepatectomy rate: Sta 48 % vs Sim 28 %
Moug et al[75]	32	32	59%	34%	Case matched study
Reddy et al[77]	475	135	17.6%	36.1%	Major hepatectomy
			10.5%	14.1%	Minor hepatectomy
de Haas[78]	173	55	25.4%	11%	3-year recurrences: Sta 63.6% vs Sim 85%

Sim: Simultaneous resection; Sta: Staged resection. The lower patient numbers in the simultaneous resection group compared with the staged resection group demonstrate a bias in patient selection. Simultaneous patients often had fewer and smaller metastases and less often underwent major hepatectomy.