Endobronchial metastasis from adenocarcinoma of gastric cardia 7 years after potentially curable resection

Figure 3 Lung tumor was immunohistologically negative for thyroid transcription factor-1 (A) and positive for caudal type homeobox transcription factor 2 (B) and hepatocyte nuclear factor-4α (C), the primary gastric carcinoma showed the same immunoreactivity (D-F) (Original magnification × 200). Thyroid transcription factor (TTF)-1: NCL-TTF-1 (Novocastra, UK, 1/100 dilution). Caudal type homeobox transcription factor (CDX)2: NCL-CDX2 (Novocastra, UK, 1/100 dilution). Hepatocyte nuclear factor-4α (HNF4α): mouse mAb H1415 (recognizing a wider range of HNF4α isoforms) (Perseus Proteomics, Tokyo, Japan, 1/100 dilution)