Current status of radiofrequency ablation of hepatocellular carcinoma

Table 3 Summary of 6 clinical studies on comparison between RFA and surgical resection

Year	Author	Study	Treatment	Patient No.	FU (mo)1	Tumor size (cm)	Overall survival (%)					P-value	Evidence3
							1 yr	2 yr	3 yr	4 yr	5 yr
2004	Vivarelli et al[51]	NR4	RFA	79	29	< 5	78	NA	33	NA	NA	0.020	2
			Resection	79			88	NA	65	NA	NA
2005	Montorsi et al[52]	NR	RFA	58	NA2	< 5	85	75	61	45	NA	0.139	2
			Resection	48			84	79	73	61	NA
2005	Hong et al[53]	NR	RFA	55	35	< 5	100	NA	74	NA	NA	0.240	2
			Resection	93			98	NA	84	NA	NA
2005	Chen et al[54]	R5	RFA	47	36	< 5	93	82	64	NA	NA	0.753	1
			Resection	65			93	86	67	NA	NA
2006	Lü et al[55]	R	RFA	51	NA	< 5	94	87	87	NA	NA	0.808	1
			Resection	54			91	86	86	NA	NA
2009	Ueno et al[56]	NR	RFA	110	36	< 5	98	NA	92	NA	63	0.060	2
			Resection	123			99	NA	92	NA	80

¹Mean follow-up period;

²Not available;

³Level of evidence;

⁴Non-randomized study;

⁵Randomized controlled study.