Intraductal papillary-mucinous neoplasia of the pancreas: Histopathology and molecular biology

Figure 1 Variation in gross appearance of intraductal papillary-mucinous neoplasm. A: Intraductal papillary-mucinous neoplasm (IPMN) involving the main pancreatic duct with copious mucus and prominent intraductal tumor proliferation causing marked dilatation of the Wirsung and Santorini ducts; B: IPMN of the main duct characterized by subtle granularity of the duct wall, little grossly visible mucin and minimal duct dilatation; C: IPMN involving clusters of dilated and mucin-filled branched ducts. Note mild distension and mucinous content of the main pancreatic duct; D: Distension of a branch duct by solid tumor tissue of an oncocytic-type IPMN.