Single-nucleus RNA sequencing and spatial transcriptomics reveal the mechanism by which Xiaozhiling injection treats internal hemorrhoids

doi:10.4240/wjgs.v17.i4.103494

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Apr 27, 2025 (publication date) through Apr 3, 2025

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Surg. Apr 27, 2025; 17(4): 103494
Published online Apr 27, 2025. doi: 10.4240/wjgs.v17.i4.103494

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Figure 4 Transmission electron microscopy. A: Transmission electron microscopy (× 5000) of eosinophils, mast cells, fibroblasts, lymphocytes, and fiber bundles 1 week after Xiaozhiling injection treatment; B: Transmission electron microscopy (× 10000) of active endoplasmic reticulum of fibroblasts 1 week after Xiaozhiling injection, with abundant glycogen attached to the endoplasmic reticulum. EOS: Eosinophil; MC: Mast cell; FB: Fibroblast; LYM: Lymphocyte; CF: Fiber bundles.

Citation: Ke MH, Huang SY, Lin WG, Xu ZG, Zheng XX, Liu XB, Cheng YM, Li ZF. Single-nucleus RNA sequencing and spatial transcriptomics reveal the mechanism by which Xiaozhiling injection treats internal hemorrhoids. World J Gastrointest Surg 2025; 17(4): 103494
URL: https://www.wjgnet.com/1948-9366/full/v17/i4/103494.htm
DOI: https://dx.doi.org/10.4240/wjgs.v17.i4.103494