Perioperative risk factors for prognosis in patients undergoing radical esophagectomy: A retrospective study

Table 1 Univariate Cox analysis of baseline characteristics for overall survival, n (%)

Baseline characteristic	n = 378	Hazard ratio	95%CI	P value
Age
<65 years	215 (56.88)	1.00	Reference	-
≥ 65 years	163 (43.12)	1.52	1.18-1.96	0.001
Gender
Male	292 (77.25)	1.00	Reference	-
Female	86 (22.75)	0.89	0.67-1.19	0.44
BMI (kg/m²), mean ± SD	23.10 ± 3.20	0.97	0.93-1.02	0.24
Hypertension
No	246 (65.08)	1.00	Reference	-
Yes	132 (34.92)	1.28	0.99-1.65	0.06
Diabetes
No	298 (78.84)	1.00	Reference	-
Yes	80 (21.16)	1.31	0.98-1.75	0.07
Smoking history
No	156 (41.27)	1.00	Reference	-
Yes	222 (58.73)	1.22	0.94-1.58	0.13
History of drinking
No	169 (44.70)	1.00	Reference	-
Yes	209 (55.29)	1.15	0.89-1.48	0.28
Chronic gastritis
No	271 (71.69)	1.00	Reference	-
Yes	107 (28.31)	1.12	0.85-1.47	0.43
ASA classification
III	312 (82.54)	1.00	Reference	-
IV	66 (17.46)	1.45	1.08-1.95	0.01
NYHA classification
I	256 (67.72)	1.00	Reference	-
II	89 (23.54)	1.33	0.99-1.78	0.06
III	33 (8.74)	1.68	1.12-2.52	0.01
Glomerular filtration rate
< 90 mL/minute/1.73 m²	142 (37.57)	1.00	Reference	-
≥ 90 mL/minute/1.73 m²	236 (62.43)	0.81	0.63-1.05	0.11

CI: Confidence interval; BMI: Body mass index; ASA: American Society of Anesthesiologists; NYHA: New York Heart Association.