Early prediction of anastomotic leakage after rectal cancer surgery: Onodera prognostic nutritional index combined with inflammation-related biomarkers

Table 3 Analysis of risk factors for anastomotic leakage

Variables	Univariate					Multivariate
	β	SE	Z	P value	OR (95%CI)	β	SE	Z	P value	OR (95%CI)
Hb	-0.021	0.006	-3.634	< 0.001	0.980 (0.969-0.991)	0.001	0.008	0.127	0.899	1.001 (0.986-1.016)
LYM	-2.251	0.400	-5.625	< 0.001	0.105 (0.048-0.231)	0.455	0.743	0.613	0.540	0.634 (0.148-2.719)
MONO	1.882	0.702	2.681	0.007	6.567 (1.659-25.995)	1.109	1.119	0.991	0.322	3.031 (0.338-27.160)
NE	0.271	0.076	3.556	< 0.001	1.312 (1.129-1.523)	0.150	0.212	0.710	0.478	0.860 (0.568-1.303)
OPNI	-0.354	0.045	-7.781	< 0.001	0.702 (0.642-0.768)	-0.350	0.048	-7.227	< 0.001	0.705 (0.641-0.775)
NLR	0.609	0.114	5.337	< 0.001	1.838 (1.470-2.298)	0.488	0.147	3.317	< 0.001	1.628 (1.221-2.172)
PLR	0.008	0.002	4.348	< 0.001	1.008 (1.004-1.012)	-0.006	0.003	-2.026	0.043	0.994 (0.989-0.999)

Hb: Hemoglobin; LYM: Lymphocytes; MONO: Monocytes; NE: Neutrophils; OPNI: Onodera prognostic nutrition index; NLR: Neutrophil-to-lymphocyte ratio; PLR: Platelet-to-lymphocyte ratio.