Early prediction of anastomotic leakage after rectal cancer surgery: Onodera prognostic nutritional index combined with inflammation-related biomarkers

Table 2 Haematological and serological indicators, n (%)

Indicators	Anastomotic leakage group (n = 49)1	No anastomotic leakage group (n = 385)1	Statistic	P value
WBC	6.00 (5.18, 7.29)	6.39 (4.63, 7.87)	9333.00	0.9052
Hb	135 (120, 148)	120 (103, 138)	12738.00	< 0.0012
Plt	244 (199, 292)	225 (195, 302)	9945.00	0.5362
LYM	1.83 (1.49, 2.23)	1.34 (1.13, 1.64)	14667.50	< 0.0012
NE	3.59 (2.88, 4.35)	4.05 (2.84, 5.76)	7957.50	0.0752
MONO	0.44 (0.34, 0.55)	0.51 (0.39, 0.64)	7374.00	0.0132
OPNI	50.5 (47.4, 53.2)	42.5 (39.3, 45.6)	16750.50	< 0.0012
NLR	1.94 (1.46, 2.59)	3.20 (2.03, 4.22)	4799.00	< 0.0012
PLR	131 (101, 173)	179 (123, 251)	5934.50	< 0.0012
CEA (%)			2.123	0.1453
Normal	238 (61.8)	25 (51.0)
High	147 (38.2)	24 (49.0)
CA199 (%)			0.002	0.9653
Normal	284 (73.8)	36 (73.5)
High	101 (26.2)	13 (26.5)

¹Median (IQR).

²Wilcoxon rank sum test.

³Pearson's χ² test.

WBC: White blood cells; Hb: Hemoglobin; Plt: Platelets; LYM: Lymphocytes; NE: Neutrophils; MONO: Monocytes; OPNI: Onodera prognostic nutrition index; NLR: Neutrophil-to-lymphocyte ratio; PLR: Platelet-to-lymphocyte ratio; CEA: Carcinoembryonic antigen; CA199: Carbohydrate antigen 199.