Early prediction of anastomotic leakage after rectal cancer surgery: Onodera prognostic nutritional index combined with inflammation-related biomarkers

Table 1 Comparison of clinical data, n (%)

Characteristic	Anastomotic leakage group (n = 49)	No anastomotic leakage group (n = 385)	Statistic	P value
Age			0.96	0.32821
< 60	173 (44.9)	18 (37.5)
≥ 60	212 (55.1)	30 (62.5)
Gender			3.66	0.05621
Male	220 (57.1)	35 (71.4)
Female	165 (42.9)	14 (28.6)
BMI				0.26232
< 18.5	11 (2.9)	4 (8.2)
18.5-24	169 (43.9)	22 (44.9)
24-28	159 (41.3)	19 (38.8)
≥ 28	46 (11.9)	4 (8.2)
Smoking			0.87	0.35221
No	268 (69.8)	31 (63.3)
Yes	116 (30.2)	18 (36.7)
Drinking			1.61	0.20421
No	308 (80.2)	43 (87.8)
Yes	76 (19.8)	6 (12.2)
History of hypertension			2.03	0.15521
No	295 (76.6)	33 (67.3)
Yes	90 (23.4)	16 (32.7)
Cardiac insufficiency				0.13332
No	371 (96.4)	45 (91.8)
Yes	14 (3.6)	4 (8.2)
History of diabetes			3.97	0.04621
No	330 (85.7)	47 (95.9)
Yes	55 (14.3)	2 (4.1)
History of abdominal surgery			0.48	0.48721
No	289 (75.1)	39 (79.6)
Yes	96 (24.9)	10 (20.4)
ASA				0.46232
1-2	369 (95.8)	46 (93.9)
3-4	16 (4.2)	3 (6.1)
Bowel obstruction				0.31332
No	366 (95.1)	45 (91.8)
Yes	19 (4.9)	4 (8.2)
Black stool			0.04	0.83921
No	163 (42.3)	20 (40.8)
Yes	222 (57.7)	29 (59.2)
Differentiated degree				> 0.99932
Poorly	33 (8.6)	4 (8.2)
Moderately	317 (82.3)	41 (83.7)
Well	35 (9.1)	4 (8.2)
Nerve invasion			1.01	0.31421
Negative	320 (83.3)	38 (77.6)
Positive	64 (16.7)	11 (22.4)
Intravascular tumor emboli			0.00	0.95521
Negative	313 (81.3)	40 (81.6)
Positive	72 (18.7)	9 (18.4)
T stage				0.46432
T1	20 (5.2)	2 (4.2)
T2	59 (15.3)	4 (8.3)
T3	281 (73.0)	37 (77.1)
T4	25 (6.5)	5 (10.4)
N stage				0.58532
N0	224 (58.2)	31 (63.3)
N1	101 (26.2)	9 (18.4)
N2	56 (14.5)	9 (18.4)
N3	4 (1.0)	0 (0.0)
Tumor stage			0.19	0.65921
1-2	223 (57.9)	30 (61.2)
3-4	162 (42.1)	19 (38.8)

¹Pearson's χ² test.

²Fisher's exact test.

BMI: Body mass index; ASA: American Society of Anesthesiologists.