Gastric adenocarcinoma of fundic gland mucosa arising in heterotopic gastric mucosa of the duodenum: A case report

Figure 2 Representative hematoxylin and eosin staining and immunohistochemical analysis images from a case involving a middle-aged male patient diagnosed with gastric adenocarcinoma of the fundic gland mucosa. A: The superficial mucosa exhibited gastric foveolar-type epithelium, numerous mucous glands were observed immediately below the epithelium; B: Scattered dilated glands were observed in the deepest region of the mucosa; C: Focal areas displayed several signet-ring cell changes (black arrow); D-I: Gastric foveolar-type epithelium was diffusely positivity for MUC5AC (D) and Ki67 (E); mucous glands were positivity for MUC6 (F), partially positive for MUC2 (G), pepsinogen I (H) and H+/K+ ATPase (I).