Retrospective Cohort Study
Copyright ©The Author(s) 2025.
World J Gastrointest Surg. Apr 27, 2025; 17(4): 100851
Published online Apr 27, 2025. doi: 10.4240/wjgs.v17.i4.100851
Table 2 Single variables affecting the occurrence of postoperative bone metastases in patients undergoing colorectal cancer surgery, n (%)
Variables

Bone metastases (n = 44)
No bone metastases (n = 56)
t/χ2
P value
Age≤ 6024 (54.55)36 (64.29)0.9740.324
> 6020 (45.45)20 (42.86)
SexMale24 (54.55)40 (71.43)3.0480.081
Female20 (45.45)16 (28.57)
The primary location of the tumorColon11 (25.00)30 (53.57)8.3150.004
Rectum33 (75.00)26 (46.43)
Tumor diameter< 5 cm31 (70.45)34 (60.71)1.0280.311
≥ 5 cm13 (29.55)22 (39.29)
Osteopathic changesOsteolytic19 (43.18)15 (26.79)2.9850.225
Osteogenic14 (31.82)22 (39.29)
Mixed bone destruction11 (25.00)19 (33.93)
Infiltration depthT1-T214 (31.82)27 (48.21)2.7380.098
T3-T430 (68.18)29 (51.79)
Postoperative chemotherapyYes11 (25.00)45 (80.36)30.644< 0.001
No33 (75.00)11 (19.64)
Combined lung metastasesYes26 (59.09)18 (32.14)7.2620.007
No18 (40.91)38 (67.86)
Concomitant liver metastasisYes11 (25.00)24 (42.86)3.4540.063
No33 (75.00)32 (57.14)
Concomitant pancreatic metastasisYes7 (15.91)11 (19.64)0.2330.630
No37 (84.09)45 (80.36)
Lymph node involvementYes29 (65.91)19 (33.93)10.0960.002
No15 (34.09)37 (66.07)