Efficacy of fluorouracil combined with paclitaxel and oxaliplatin for the treatment of advanced gastric signet ring cell carcinoma

Table 2 Analysis of the relationship between serum index expression levels and treatment efficacy before and after chemotherapy (mean ± SD)

Detect items	Patients with PR (n = 22)		Patients with SD (n = 40)		Patients with PD (n = 23)		P value
	Before chemotherapy	After chemotherapy	Before chemotherapy	After chemotherapy	Before chemotherapy	After chemotherapy
CEA (ng/mL)	28.5 ± 27.8	22.6 ± 21.6	24.8 ± 25.7	23.4 ± 22.5	32.8 ± 31.8	44.6 ± 34.8	< 0.01
CA19-9 (ng/mL)	145 ± 117	116 ± 91	159 ± 127	164 ± 136	166 ± 115	186 ± 145	< 0.01
Serum albumin (g/L)	267 ± 155	278 ± 193	409 ± 267	405 ± 260	470 ± 258	413 ± 256	< 0.01
Serum total protein (g/L)	569 ± 385	509 ± 314	548 ± 256	526 ± 215	587 ± 258	596 ± 274	> 0.05

CA19-9: Carbohydrate antigen 19-9; CEA: Carcinoembryonic antigen; PD: Progressive disease; PR: Partial remission; SD: Stable disease.