Prognostic value of combined detection of alpha-fetoprotein, plasma prothrombin activity, and serum prealbumin in acute-on-chronic liver failure

Table 4 Diagnostic value of alpha-fetoprotein + prothrombin activity + prealbumin detection for prognosis of acute-on-chronic liver failure patients

Indicators	Sensitivity (%)	Specificity (%)	Youden index	Cut-off	AUC	95%CI
AFP (ng/mL)	80.00	100.00	0.800	99.080	0.907	0.839-0.976
PTA (μg/L)	74.50	87.50	0.620	30.795	0.849	0.766-0.931
PA (mg/L)	70.20	95.50	0.652	78.235	0.853	0.773-0.933
Joint detection	95.70	95.50	0.907	-	0.989	0.974-1.000

AFP: Alpha-fetoprotein; PTA: Prothrombin activity; PA: Prealbumin; AUC: Area under the curve; CI: Confidence interval.