Gamma-glutamyl transferase-to-lymphocyte ratio as a prognostic marker in patients with hepatocellular carcinoma undergoing hepatectomy

doi:10.4240/wjgs.v17.i2.98578

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Surg. Feb 27, 2025; 17(2): 98578
Published online Feb 27, 2025. doi: 10.4240/wjgs.v17.i2.98578

Table 3 Multivariate analysis of different factors for overall survival

Variables	HR (95%CI)	P value
Age (year)	0.977 (0.956-0.998)	0.024^a
ALT (U/L)	0.995 (0.992-0.997)	0.185
ALB (g/L)	0.961 (0.907-0.995)	0.151
TBIL (μmol/L)	1.035 (1.008-1.070)	0.045^a
DBIL (μmol/L)	0.949 (0.918-0.982)	0.103
PLR	0.995 (0.991-0.997)	< 0.001^a
Postoperative TACE	0.443 (0.325-0.601)	0.001^a
Child-Pugh grade	0.655 (0.525-0.849)	0.006^a
Sex, month
0-13	2.639 (1.234-3.508)	0.024^a
14-26	1.908 (0.732-2.498)	0.168
> 26	0.383 (0.100-0.722)	0.552
GLR, month
0-13	1.002 (1.002-1.005)	0.022^a
14-26	1.008 (1.004-1.010)	< 0.001^a
> 26	1.011 (1.007-1.014)	< 0.001^a
MVI, month
0-13	2.166 (1.295-3.613)	0.003^a
14-26	1.254 (0.783-2.010)	0.381
> 26	0.510 (0.188-1.386)	0.187
Degree of differentiation, month
0-13	0.354 (0.223-0.561)	< 0.001^a
14-26	0.541 (0.332-0.881)	0.004^a
> 26	0.910 (0.506-1.639)	0.591

^aP < 0.05.

ALB: Albumin; ALT: Alanine aminotransferase; CI: Confidence interval; DBIL: Direct bilirubin; GLR: Gamma-glutamyl transferase-to-lymphocyte ratio; HR: Hazard ratio; MVI: Microvascular invasion; PLR: Platelet-to-lymphocyte ratio; TACE: Transarterial chemoembolization; TBIL: Total bilirubin.

Citation: Zhou PC, Huang R, Wang HT, Yang J, Peng JD, Fu ZX, Liao WJ, Ma HQ, Wu LQ, Li EL. Gamma-glutamyl transferase-to-lymphocyte ratio as a prognostic marker in patients with hepatocellular carcinoma undergoing hepatectomy. World J Gastrointest Surg 2025; 17(2): 98578
URL: https://www.wjgnet.com/1948-9366/full/v17/i2/98578.htm
DOI: https://dx.doi.org/10.4240/wjgs.v17.i2.98578