Predictive value of C-reactive protein, procalcitonin, and total bilirubin levels for pancreatic fistula after gastrectomy for gastric cancer

Table 3 Univariate analysis of factors affecting the development of a pancreatic fistula following radical gastrectomy for gastric cancer, mean ± SD

Factors	Groups	Pancreatic fistula group (n = 31)	Non-pancreatic fistula group (n = 127)	t/χ2 value	P value
Age (years)	≥ 60	20	71	0.756	0.384
	< 60	11	56
Sex	Male	18	70	0.088	0.767
	Female	13	57
Diabetes	Yes	16	30	9.460	0.002
	No	15	97
Hypertension	Yes	6	21	0.140	0.708
	No	25	106
Hyperlipidemia	Yes	13	16	14.311	0.000
	No	18	111
Hemoglobin (g/L)	Normal	29	117	0.012	0.912
	Descend	2	10
Albumin (g/L)	Normal	29	121	0.004	0.949
	Descend	2	6
History of abdominal surgery	Yes	3	7	0.196	0.658
	No	28	120
Operative time (hour)	≤ 3	19	84	0.258	0.611
	> 3	12	43
Intraoperative pancreatic injury	Yes	14	16	17.177	0.000
	No	17	111
Combined splenectomy	Yes	4	2	4.785	0.029
	No	27	125
Combined splenectomy and partial pancreatectomy	Yes	2	2	0.832	0.362
	No	29	125
Retro-pancreatic lymph node dissection	Yes	19	60	1.967	0.161
	No	12	67
Scope of gastric resection	Proximal stomach	4	18	0.080	0.961
	Distal stomach	18	75
	Whole stomach	9	34
Post-operative pathological staging	I-II	12	51	0.022	0.883
	III-IV	19	76
Serum PCT level on day 1 post-surgery (g/mL)		0.99 ± 0.33	0.71 ± 0.11	8.020	0.000
Serum CRP level on day 1 post-surgery (mg/L)		173.14 ± 32.45	106.69 ± 20.46	14.266	0.000
Serum TBil level on day 1 post-surgery (μmol/L)		20.83 ± 4.18	17.69 ± 4.13	3.786	0.000

Hemoglobin levels are considered normal at ≥ 110 g/L; Albumin levels are considered normal at ≥ 35 g/L. CRP: C-reactive protein; PCT: Procalcitonin; TBil: Total bilirubin.