Predictive value of magnetic resonance imaging parameters combined with tumor markers for rectal cancer recurrence risk after surgery

Table 1 Difference analysis between high recurrence risk group and low recurrence risk group

Variables	Total (n = 90)	LRR group (n = 53)	HRR group (n = 37)	Statistic	P value
Age (year), mean ± SD	64.92 ± 10.44	64.66 ± 10.98	65.30 ± 9.75	t = -0.28	0.778
Sex, n (%)				χ² = 1.79	0.180
Female	29 (32.22)	20 (37.74)	9 (24.32)	-	-
Male	61 (67.78)	33 (62.26)	28 (75.68)	-	-
BMI, mean ± SD	25.31 ± 2.90	25.08 ± 2.90	25.63 ± 2.92	t = -0.88	0.380
Smoking, n (%)				χ² = 0.37	0.541
No	65 (72.22)	37 (69.81)	28 (75.68)	-	-
Yes	25 (27.78)	16 (30.19)	9 (24.32)	-	-
Drinking, n (%)				χ² = 0.11	0.737
No	59 (65.56)	34 (64.15)	25 (67.57)	-	-
Yes	31 (34.44)	19 (35.85)	12 (32.43)	-	-
Family history, n (%)				χ² = 0.00	1.000
No	80 (88.89)	47 (88.68)	33 (89.19)	-	-
Yes	10 (11.11)	6 (11.32)	4 (10.81)	-	-
Complication, n (%)				χ² = 0.32	0.571
No	47 (52.22)	29 (54.72)	18 (48.65)	-	-
Yes	43 (47.78)	24 (45.28)	19 (51.35)	-	-
MTL, mean ± SD	3.98 ± 1.29	3.82 ± 1.30	4.22 ± 1.25	t = -1.48	0.141
Tumor location, n (%)				χ² = 0.48	0.787
Low	32 (35.56)	20 (37.74)	12 (32.43)	-	-
Median	39 (43.33)	23 (43.40)	16 (43.24)	-	-
High	19 (21.11)	10 (18.87)	9 (24.32)	-	-
MrT staging, n (%)				χ² = 2.81	0.094
I or II	46 (51.11)	31 (58.49)	15 (40.54)	-	-
III or IV	44 (48.89)	22 (41.51)	22 (59.46)	-	-
MrN staging, n (%)				χ² = 4.43	0.035
0 or I	46 (51.11)	32 (60.38)	14 (37.84)	-	-
II or III	44 (48.89)	21 (39.62)	23 (62.16)	-	-
CRM, n (%)				χ² = 8.25	0.004
Negative	38 (42.22)	29 (54.72)	9 (24.32)	-	-
Positive	52 (57.78)	24 (45.28)	28 (75.68)	-	-
EMVI, n (%)	-	-	-	χ² = 4.50	0.034
Negative	60 (66.67)	40 (75.47)	20 (54.05)	-	-
Positive	30 (33.33)	13 (24.53)	17 (45.95)	-	-
CEA, mean ± SD	40.08 ± 11.25	35.57 ± 9.31	46.55 ± 10.71	t = -5.17	< 0.001
CA125, mean ± SD	11.72 ± 5.25	11.07 ± 5.28	12.66 ± 5.13	t = -1.42	0.160
CA199, mean ± SD	56.58 ± 11.18	50.44 ± 7.85	65.39 ± 9.19	t = -8.29	< 0.001

BMI: Body mass index; LRR: Low recurrence risk; HRR: High recurrence risk; MTL: Maximum tumor length; CRM: Circumferential resection margin; EMVI: Extramural vascular invasion; CEA: Carcinoembryonic antigen; CA: Carbohydrate antigen.