Synergistic inhibition of colorectal cancer progression by silencing Aurora A and the targeting protein for Xklp2

Figure 3 Aurora A and targeting protein for Xklp2 are high expressed in human colonic adenocarcinoma tissue. A: The Aurora kinase A (AURKA) expression in colonic adenocarcinoma (COAD) tissue was increased compared to normal tissues; B: The targeting protein for Xklp2 expression in COAD tissue was increased compared to normal tissues. The expression level analysis results are from gene expression profiling interactive analysis; C: Expression of the AURKA protein in human COAD tissue sample or normal colon. The normal colon tissue photos from (https://www.proteinatlas.org/ENSG00000087586-AURKA/tissue/colonimg); the COAD tissue photos from the human protein atlas (https://www.proteinatlas.org/ENSG00000087586-AURKA/pathology/colorectal+cancerimg). ^aP < 0.05. AURKA: Aurora kinase A; TPX2: Targeting protein for Xklp2; COAD: Colonic adenocarcinoma; CRC: Colorectal cancer; T: Tumors; N: Normal.