Diagnostic value of serum vascular endothelial growth factor and interleukin-17 in primary hepatocellular carcinoma

Table 2 Comparison of serum vascular endothelial growth factor and interleukin-17 levels in different pathological characteristics of the study groups

Factor	Classification	Cases	VEGF (pg/mL)	P value	IL-17 (pg/mL)	P value
Gender	Male	35	264.90 ± 113.04	0.800	36.15 ± 13.26	0.228
	Female	15	274.17 ± 128.28		37.06 ± 12.07
Age	< 50 years old	36	275.39 ± 107.69	0.467	35.83 ± 11.95	0.606
	≥ 50 years old	14	248.37 ± 139.08		37.94 ± 15.15
Histological classification	Hepatocellular type	41	268.75 ± 109.59	0.892	37.00 ± 13.15	0.504
	Cholangiocyte type	9	262.83 ± 152.11		33.81 ± 11.35
TNM stage	Stage I + Stage II	19	217.72 ± 97.70	0.016	28.44 ± 11.25	< 0.001
	Stage III + Stage IV	31	298.30 ± 117.96		41.32 ± 11.25
Tumor diameter	> 5 cm	21	255.59 ± 112.66	0.538	38.93 ± 12.72	0.243
	≤ 5 cm	29	276.44 ± 120.51		34.61 ± 12.76
Combined cirrhosis	Yes	28	249.73 ± 114.81	0.223	34.64 ± 12.43	0.271
	No	22	290.53 ± 117.38		38.69 ± 13.18
Degree of differentiation	Highly differentiated	27	277.33 ± 111.53	0.532	37.78 ± 13.15	0.418
	Low differentiation	23	256.35 ± 123.74		34.82 ± 12.47
Tumor metastasis	Yes	24	304.50 ± 117.44	0.030	43.79 ± 10.90	< 0.001
	No	26	233.69 ± 106.95		29.91 ± 10.94

VEGF: Vascular endothelial growth factor; IL: Interleukin.