Evaluation and analysis of neurocognitive dysfunction in patients with colorectal cancer after radical resection: A retrospective study

Table 3 Comparison of clinical data between the modeling group and external validation group, n (%)

Variables	Modeling group (n = 227)	Verification group (n = 30)	χ2/Z	P value
General information
Age [years, M (IQR)]	64 (58-69)	68.5 (65-71.5)	64 (58-69)
Sex
Male	147 (64.8)	16 (46.7)	1.491	0.222
Female	80 (35.2)	14 (53.3)
BMI [kg/m², M (IQR)]	22.3 (20.5-24.6)	23.1 (21.48-25.8)	-1.329	0.184
Years of education [year, M (IQR)]	9 (6-12)	8.5 (5-12)	-0.789	0.430
Medical history data
Hb [g/L, M (IQR)]	128 (113-138)	110 (99.75-126)	-3.368	0.001
Diabetes
No	195 (85.9)	26 (86.7)	0.013	0.91
Yes	32 (14.1)	4 (13.3)
Hypertension
No	162 (71.4)	23 (76.7)	0.369	0.543
Yes	65 (28.6)	7 (23.3)
Coronary heart disease
No	214 (94.3)	28 (93.3	7.848	0.837
Yes	13 (5.7)	2 (6.7)
Surgical data
Baseline tSO2 (%, mean ± SD)	63.81 ± 5.62	64.58 ± 6.04	2.317	0.721
Intraoperative rScO2 [%, M (IQR)]	56 (52.5-60)	58.5 (55.87-61)	-2.253	0.024
Intraoperative blood loss [mL, M (IQR)]	100 (50-150)	100 (50-200)	-0.969	0.332
DNR
No	192 (84.6)	27 (90.0)	0.617	0.432
Yes	35 (15.4)	3 (10.0)

DNR: Delayed postoperative neurocognitive recovery; IQR: Interquartile range; Hb: Hemoglobin; rScO₂: Regional cerebral saturation oxygenation; ScO₂: Cerebral regional oxygen saturation; M: Median number; tSO₂: Tissue oxygen saturation.