Evaluation and analysis of neurocognitive dysfunction in patients with colorectal cancer after radical resection: A retrospective study

Table 1 Comparison of clinical data between the delayed postoperative neurocognitive recovery group and non- delayed postoperative neurocognitive recovery group, n (%)

Variable	DNR group (n = 35)	Non DNR group (n = 192)	χ2/Z	P value
General information
Age [years, M (IQR)]	69 (63-72)	63 (57-68)	-3.077	0.002
Sex
Male	27 (77.1)	120 (62.5)	2.781	0.095
Female	8 (22.9)	72 (37.5)
BMI (kg/m², mean ± SD)	22.65 ± 2.30	22.68 ± 2.98	4.191	0.042
Years of education [year, M (IQR)]	7 (6-9)	9 (6-12)	-2.308	0.021
Preoperative medical history data
Hb [g/L, M (IQR)]	128 (115-136)	128 (112-139)	-0.322	-0.322
MMSE score, M (IQR)	28 (26-29)	29 (27-30)	-1.23	-1.23
Diabetes
No	26 (74.3)	169 (88.0)	4.612	0.612
Yes	9 (25.7.0)	23 (12.0)
Hypertension
No	27 (77.1)	135 (70.3)	0.676	0.676
Yes	8 (22.9)	57 (29.7)
Coronary heart disease
No	32 (91.4)	182 (94.8)	0.62	0.62
Yes	3 (8.6)	10 (5.2)
Surgical data
Baseline rScO2	62.89 ± 6.05	64.74 ± 5.18	1.452	0.456
ScO2, M (IQR)	54.5 (52-58.5)	56.5 (53-60)	-1.813	0.070
Intraoperative blood loss [mL, M (IQR)]	100 (100-200)	100 (50-150)	-2.641	0.008
Anesthesia time (minute)	281.31 ± 72.95	267.09 ± 75.74	0.742	0.390
Surgical time (minute)	210.77 ± 65.28	197.43 ± 69.37	0.145	0.704
Laparoscopic conversion to open abdominal surgery	2 (5.7)	13 (6.8)	0.054	0.817

DNR: Delayed postoperative neurocognitive recovery; MMSE: Mini mental state examination; IQR: Interquartile range; Hb: Hemoglobin; rScO₂: Regional cerebral saturation oxygenation; ScO₂: Cerebral regional oxygen saturation; M: Median number.