Analysis of alkaline phosphatase and γ-glutamyltransferase after radiofrequency ablation of primary liver cancer: A retrospective study

Table 4 Relationship between serum alkaline phosphatase and γ-glutamyltransferase levels before treatment and clinical characteristics

Project	ALP ≤ 135 U/L (n = 127)	ALP > 135 U/L (n = 38)	χ2	P value	GGT ≤ 45 U/L (n = 65)	GGT > 45 U/L (n = 100)	χ2	P value
Age (< 60 years vs ≥ 60 years)	68/59	24/14	1.096	0.295	32/33	60/40	1.852	0.174
Gender (female vs male)	102/25	24/14	4.770	0.029	49/16	77/23	0.057	0.811
Tumor staging (0/A/B vs C/D)	103/24	29/9	0.419	0.518	58/7	74/26	6.188	0.013
Child-Puch grading (A vs B/C)	118/9	18/20	41.881	< 0.001	50/62	74/26	12.436	< 0.001
Tumor size (< 5 cm vs ≥ 5 cm)	92/35	27/11	0.028	0.867	54/11	65/35	6.402	0.011
Number of tumors (single vs multiple)	66/61	20/18	0.005	0.943	38/27	48/52	1.728	0.189
Lymph node metastasis (Y vs N)	16/111	7/31	0.827	0.363	5/60	18/82	3.489	0.062
Remote metastasis (Y vs N)	10/117	1/37	1.292	0.256	3/62	8/92	0.725	0.394
Hepatic encephalopathy (Y vs N)	4/123	3/35	1.621	0.203	0/65	7/93	4.752	0.029
Ascites (Y vs N)	22/105	16/22	10.134	0.001	12/53	26/74	1.263	0.26
Portal vein cancer thrombus (Y vs N)	6/121	2/36	0.018	0.892	1/64	7/93	2.547	0.111

AST: Aspartate aminotransferase; ALT: Alanine aminotransferase; ALP: Alkaline phosphatase; GGT: γ-glutamyltransferase.