Management of distal cholangiocarcinoma with arterial involvement: Systematic review and case series on the role of neoadjuvant therapy

Table 1 National Comprehensive Cancer Network Criteria defining resectablity at diagnosis for pancreatic ductal adenocarcinoma

Resectability status	Arterial	Venous
Resectable	No arterial tumour contact (CA, SMA, or CHA)	No tumour contacts with the SMV or PV or ≤ 180° contact without vein contour irregularity
Borderline resectable	Pancreatic head/uncinate process: (1) Solid tumour contact with CHA without extension to the CA or hepatic artery bifurcation allowing for safe and complete resection and reconstruction; (2) Solid tumour contact with the SMA of ≤ 180°; and (3) Solid tumour contact with variant arterial anatomy, and the presence and degree of tumour contact should be noted if present, as it may affect surgical planning. Pancreatic body/tail: Solid tumour contact with the CA of ≤ 180°	Solid tumour contact with the SMV or PV of > 180°, contact of ≤ 180° with contour irregularity of the vein or thrombosis of the vein but with suitable vessel proximal and distal to the site of involvement allowing for safe and complete resection and vein reconstruction: Solid tumour contact with the IVC
Locally advanced	Pancreatic head/uncinate process: Solid tumour with > 180° degrees contact with SMA or CA. Pancreatic body/tail: (1) Solid tumour contact > 180° with the SMA or CA; and (2) Solid tumour contact with CA and aortic involvement	Unreconstructible SMV or PV due to tumour involvement or occlusion (thrombus tumour)

CA: Coeliac axis; SMA: Superior mesenteric artery; CHA: Common hepatic artery; SMV: Superior mesenteric vein; PV: Portal vein; IVC: Inferior vena cava.