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©The Author(s) 2024.
World J Gastrointest Surg. Aug 27, 2024; 16(8): 2555-2564
Published online Aug 27, 2024. doi: 10.4240/wjgs.v16.i8.2555
Published online Aug 27, 2024. doi: 10.4240/wjgs.v16.i8.2555
Table 1 Patients’ characteristics (n = 85)
| TMPRSS4 expression | P value | ||
| Positivity (n = 46) | Negativity (n = 39) | ||
| Age, median (range), years | 75 (47-86) | 75 (57-87) | 0.612 |
| Sex, male, n (%) | 23 (50) | 22 (56) | 0.555 |
| Neoadjuvant chemotherapy, n (%) | 2 (4) | 1 (2) | 0.653 |
| Preoperative CA19-9 level, median (range), U/mL | 37 (0-27146) | 13 (0-1246) | 0.019 |
| Diseases, n (%) | |||
| Perihilar cholangiocarcinoma | 8 (17) | 6 (15) | 0.176 |
| Distal cholangiocarcinoma | 10 (22) | 13 (34) | |
| Gallbladder cancer | 19 (41) | 18 (46) | |
| Ampulla of vater cancer | 9 (20) | 2 (5) | |
| Operating time, median (range), min | 465 (82-962) | 425 (239-1052) | 0.853 |
| Operative blood loss, median (range), mL | 310 (5-3950) | 410 (5-1600) | 0.609 |
| Histology, tub1/tub2, n (%) | 37 (80) | 31 (79) | 0.913 |
| Tumor stage, pT3/T4, n (%) | 14 (30) | 10 (26) | 0.624 |
| Pathological tumor size, median (range), mm | 35 (0-110) | 25 (1-88) | 0.081 |
| Lymphatic invasion (ly), n (%) | 16 (35) | 6 (15) | 0.039 |
| Venous invasion (v), n (%) | 20 (43) | 14 (36) | 0.477 |
| Neural invasion (ne), n (%) | 22 (48) | 17 (44) | 0.696 |
| Tumor infiltrative type c (IFN c), n (%) | 8 (17) | 5 (13) | 0.558 |
| Lymph node metastasis, n (%) | 24 (52) | 16 (41) | 0.304 |
| Resection status, R0, n (%) | 36 (78) | 31 (80) | 0.890 |
| Adjuvant chemotherapy, n (%) | 27 (59) | 22 (56) | 0.832 |
- Citation: Shibata Y, Sudo T, Tazuma S, Tanimine N, Onoe T, Shimizu Y, Yamaguchi A, Kuraoka K, Takahashi S, Tashiro H. Transmembrane serine protease 4 expression in the prognosis of radical resection for biliary tract cancer. World J Gastrointest Surg 2024; 16(8): 2555-2564
- URL: https://www.wjgnet.com/1948-9366/full/v16/i8/2555.htm
- DOI: https://dx.doi.org/10.4240/wjgs.v16.i8.2555