Energy spectrum computed tomography multi-parameter imaging in preoperative assessment of vascular and neuroinvasive status in gastric cancer

Table 3 Prediction efficacy of spectral computed tomography parameters for vascular nerve invasion status in gastric cancer

Project	AUC (95%CI)	Youden index	Optimal threshold	Sensitivity (%)	Specificity (%)
Arterial phase
CT (HU)	0.755 (0.637-0.873)	0.498	196.0	54.76	95.00
CT (HU)	0.793 (0.837-0.977)	0.545	84.5	59.52	95.00
K (₄n)	0.725 (0.602-0.848)	0.450	3.7	50.00	95.00
IC (× 100 μg/cm³)	0.726 (0.602-0.849)	0.450	19.5	50.00	95.00
NIC	0.727 (0.593-0.862)	0.517	0.1	66.67	85.00
AP-all	0.845 (0.747-0.943)	0.548	0.9	54.76	100.00
Venous phase
CTk (HU)	0.830 (0.720-0.941)	0.633	217.6	83.33	80.00
CT (HU)	0.907 (0.837-0.977)	0.710	92.4	80.95	90.00
K	0.740 (0.606-0.875)	0.405	4.1	90.48	50.00
IC (× 100μg/cm³)	0.742 (0.607-0.876)	0.405	21.8	90.48	50.00
NIC	0.745 (0.604-0.886)	462	0.5	76.19	70.00
VP-all	0.931 (0.872-0.990)	0.760	0.7	80.95	95.00
Delay period
CT (HU)	0.560 (0.406-0.713)	0.179	155.9	92.86	25.00
CT (HU)	0.708 (0.573-0.843)	0.386	74.3	78.57	60.00
K	0.529 (0.371-0.686)	0.105	3.0	90.48	20.00
IC (× 100 μg/cm³)	0.532 (0.375-0.690)	0.081	15.9	88.10	20.00
NIC	0.702 (0.560-0.845)	0.412	0.5	76.19	65.00
DP-all	0.719 (0.584-0.854)	0.374	0.7	52.38	85.00

AUC: Area under the curve; CT: Computed tomography; IC: Iodine concentration; NIC: Normalized iodine concentration.