Multidisciplinary management of ulcerative colitis complicated by immune checkpoint inhibitor-associated colitis with life-threatening gastrointestinal hemorrhage: A case report

Figure 3 Pathology of the sigmoidoscopic biopsy specimen. A: Ulcer formation: Surface inflammatory exudation necrosis, underlying granulation tissue hyperplasia, interstitial "transmural" hybrid inflammatory cell infiltration, hematoxylin and eosin (HE) staining × 40; B: Cryptitis, crypt abscesses (yellow arrow), and significantly increased numbers of apoptotic cells (blue arrows), HE × 400.