Therapeutic effects of Buzhong Yiqi decoction in patients with spleen and stomach qi deficiency after routine surgery and chemotherapy for colorectal cancer

Table 4 Comparison of inflammatory mediators before and after treatment between the two groups (mean ± SD)

Index		Control group (n = 50)	Observation group (n = 50)	t value	P value
IL-10 (ng/L)	1 d preoperatively	8.73 ± 1.97	8.62 ± 2.01	1.012	0.849
	14 d postoperatively	10.21 ± 2.14a	15.32 ± 2.43a	11.311	< 0.001
IL-6 (ng/L)	1 d preoperatively	7.41 ± 1.16	7.29 ± 1.07	0.190	0.314
	14 d postoperatively	20.78 ± 3.46a	16.72 ± 3.28a	5.733	< 0.001
TNF-α (ng/mL)	1 d preoperatively	18.21 ± 4.21	18.73 ± 4.56	0.701	0.485
	14 d postoperatively	34.32 ± 5.02a	22.31 ± 4.94a	12.060	< 0.001
CRP (mg/L)	1 d preoperatively	6.45 ± 0.37	6.53 ± 0.34	1.802	0.075
	14 d postoperatively	31.68 ± 3.72a	19.27 ± 3.45a	17.097	< 0.001

^aP < 0.05 vs before treatment.

CRP: C-reactive protein; IL-6: Interleukin-6; IL-10: Interleukin-10; TNF-α: Tumor necrosis factor-alpha.