Diagnostic significance of serum levels of serum amyloid A, procalcitonin, and high-mobility group box 1 in identifying necrotising enterocolitis in newborns

Table 3 Comparison of serum amyloid A, procalcitonin, and high-mobility group box 1 between the two groups

Parameter	Healthy newborns (n = 50)	NEC group (n = 48)	t value	P value
Serum SAA (mg/L)	11.12 ± 3.52	15.67 ± 3.28	6.625	< 0.001
Serum PCT (ng/mL)	2.35 ± 1.15	4.22 ± 1.56	6.754	< 0.001
Serum HMGB1 (ng/mL)	54.54 ± 10.28	68.93 ± 10.03	7.012	< 0.001

SSA: Serum amyloid A; PCT: Procalcitonin; HMGB1: High-mobility group box 1; NEC: Necrotising enterocolitis.