FDX1 as a novel biomarker and treatment target for stomach adenocarcinoma

Table 4 Univariate/multivariate Cox regression

Characteristics	Total (n)	Univariate analysis		Multivariate analysis
		Hazard ratio (95%CI)	P value	Hazard ratio (95%CI)	P value
FDX1	370
High	184	Reference
Low	186	1.282 (0.922-1.784)	0.140
LIAS	370
High	183	Reference
Low	187	1.501 (1.075-2.095)	0.017	1.414 (0.981-2.038)	0.063
MTF1	370
High	185	Reference
Low	185	1.368 (0.985-1.900)	0.061	1.346 (0.936-1.936)	0.109
T stage	362
T1	18	Reference
T2	78	6.725 (0.913-49.524)	0.061	4.323 (0.548-34.111)	0.165
T3	167	9.548 (1.326-68.748)	0.025	5.338 (0.613-46.515)	0.129
T4	99	9.634 (1.323-70.151)	0.025	5.141 (0.576-45.881)	0.143
N stage	352
N0	107	Reference
N1	97	1.629 (1.001-2.649)	0.049	1.152 (0.578-2.296)	0.688
N2	74	1.655 (0.979-2.797)	0.060	1.298 (0.553-3.050)	0.549
N3	74	2.709 (1.669-4.396)	< 0.001	1.818 (0.772-4.281)	0.171
M stage	352
M0	327	Reference
M1	25	2.254 (1.295-3.924)	0.004	1.038 (0.430-2.504)	0.935
Pathologic stage	347
Stage I	50	Reference
Stage II	110	1.551 (0.782-3.078)	0.209	1.132 (0.399-3.212)	0.816
Stage III	149	2.381 (1.256-4.515)	0.008	1.181 (0.304-4.588)	0.810
Stage IV	38	3.991 (1.944-8.192)	< 0.001	2.082 (0.513-8.445)	0.305