FDX1 as a novel biomarker and treatment target for stomach adenocarcinoma

doi:10.4240/wjgs.v16.i6.1803

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Jun 27, 2024 (publication date) through Jun 30, 2024

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Clinical and Translational Research

World J Gastrointest Surg. Jun 27, 2024; 16(6): 1803-1824
Published online Jun 27, 2024. doi: 10.4240/wjgs.v16.i6.1803

Table 3 Gene Set Enrichment Analysis enrichment analysis results

ID	Enrichment score	NES	P value	Q values
HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION	0.708105259	2.990707978	0.001305483	0.008457298
HALLMARK_HYPOXIA	0.403129656	1.699699999	0.00130719	0.008457298
HALLMARK_APICAL_JUNCTION	0.461587301	1.935939035	0.001310616	0.008457298
HALLMARK_MYOGENESIS	0.66612	2.752470842	0.001331558	0.008457298
HALLMARK_COAGULATION	0.50179623	1.942687567	0.00143472	0.008457298
HALLMARK_UV_RESPONSE_DN	0.406876695	1.662984536	0.002702703	0.009857419
hallmark_interferon_alpha_response	-0.423867587	-1.8197451	0.003257329	0.009857419
HALLMARK_G2M_CHECKPOINT	-0.566300626	-2.681102853	0.004255319	0.009857419
hallmark_interferon_gamma_response	-0.329292011	-1.559005425	0.004255319	0.009857419
HALLMARK_E2F_TARGETS	-0.562672699	-2.6759039	0.004329004	0.009857419
HALLMARK_MYC_TARGETS_V1	-0.454693047	-2.162384814	0.004329004	0.009857419
HALLMARK_MITOTIC_SPINDLE	-0.367141984	-1.748758241	0.004347826	0.009857419
HALLMARK_MTORC1_SIGNALING	-0.385874626	-1.837984926	0.004347826	0.009857419
HALLMARK_MYC_TARGETS_V2	-0.448665513	-1.728129282	0.005617978	0.011827321
HALLMARK_INFLAMMATORY_RESPONSE	-0.318801368	-1.472576393	0.00862069	0.016938899
HALLMARK_PROTEIN_SECRETION	-0.367157298	-1.567228573	0.009771987	0.018001029
HALLMARK_ANGIOGENESIS	0.547725076	1.690092924	0.014802632	0.025664005
HALLMARK_IL6_JAK_STAT3_SIGNALING	-0.367388389	-1.508170458	0.018181818	0.029771398
HALLMARK_KRAS_SIGNALING_DN	0.371059103	1.431772189	0.024425287	0.037786775
hallmark_estrogen_response_late	-0.291604703	-1.348128819	0.025641026	0.037786775
HALLMARK_UNFOLDED_PROTEIN_RESPONSE	-0.323403998	-1.423443484	0.029315961	0.041145208
HALLMARK_HEDGEHOG_SIGNALING	0.472117157	1.469309232	0.045602606	0.0610944

Citation: Xie XZ, Zuo L, Huang W, Fan QM, Weng YY, Yao WD, Jiang JL, Jin JQ. FDX1 as a novel biomarker and treatment target for stomach adenocarcinoma. World J Gastrointest Surg 2024; 16(6): 1803-1824
URL: https://www.wjgnet.com/1948-9366/full/v16/i6/1803.htm
DOI: https://dx.doi.org/10.4240/wjgs.v16.i6.1803