Prediction and analysis of albumin-bilirubin score combined with liver function index and carcinoembryonic antigen on liver metastasis of colorectal cancer

doi:10.4240/wjgs.v16.i6.1670

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Surg. Jun 27, 2024; 16(6): 1670-1680
Published online Jun 27, 2024. doi: 10.4240/wjgs.v16.i6.1670

Table 2 Baseline data between modeling group and validation group (n = 195)

Index	Modeling group (n = 130)	Validation group (n = 65)	P value
Age (mean ± SD, yr)	60.3 ± 11.8	60.8 ± 31.2	0.772
Gender, n (%)			0.473
Man	73 (56.2)	40 (61.5)
Female	57 (43.8)	25 (38.5)
Primary tumor location, n (%)			0.222
Colon	62 (47.7)	25 (38.5)
Rectum	68 (52.3)	40 (61.5)
BMI, M (P₂₅, P₇₅), kg/m²	22.3 (20.3, 24.9)	22.0 (20.6, 25.0)	0.992
TBIL, M (P₂₅, P₇₅), μmol/L	13.3 (10.2, 18.0)	14.0 (9.6, 18.7)	0.825
DBIL, M (P₂₅, P₇₅), μmol/L	4.7 (2.8, 7.3)	3.9 (2.7, 7.1)	0.462
IBIL, M (P₂₅, P₇₅), μmol/L	8.7 (5.5, 11.9)	9.6 (5.6, 13.0)	0.412
ALT, M (P₂₅, P₇₅), U/L	17.5 (11.0, 31.0)	20.0 (11.0, 33.0)	0.518
AST, M (P₂₅, P₇₅), U/L	24.5 (17.0, 36.0)	24.0 (17.5, 38.0)	0.846
AST/ALT, M (P₂₅, P₇₅)	1.4 (0.9, 1.8)	1.4 (0.9, 1.9)	0.715
TP, M (P₂₅, P₇₅), g/L	68.3 (63.8, 72.9)	67.1 (61.8, 73.0)	0.348
ALB, M (P₂₅, P₇₅), g/L	40.1 (35.8, 43.5)	39.1 (36.8, 42.7)	0.666
GLO, M (P₂₅, P₇₅), g/L	28.7 (24.4, 32.4)	28.4 (24.0, 31.4)	0.556
A/G (mean ± SD)	1.4 ± 0.4	1.4 ± 0.3	0.991
GGT, M (P₂₅, P₇₅), U/L	22.5 (14.0, 52.3)	22.0 (14.5, 40.5)	0.828
ALP, M (P₂₅, P₇₅), U/L	80.0 (63.8, 111.0)	86.0 (67.0, 110.0)	0.606
AFP, M (P₂₅, P₇₅), μg/L	2.5 (1.7, 3.3)	2.7 (1.6,3.2)	0.607
CEA, M (P₂₅, P₇₅), μg/L	4.7 (2.0, 33.3)	5.3 (2.5, 35.3)	0.514
CA125, M (P₂₅, P₇₅), U/mL	12.6 (8.6, 23.2)	31.2 (9.1, 22.7)	0.792
CA19-9, M (P₂₅, P₇₅), U/mL	13.9 (8.1, 52.6)	15.2 (8.2, 52.4)	0.697
ALBI score, M (P₂₅, P₇₅)	-2.7 (-2.9, -2.3)	-2.7 (-2.9, -2.4)	0.522

BMI: Body mass index; TBIL: Total bilirubin; DBIL: Direct bilirubin; IBIL: Indirect bilirubin; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; TP: Total protein; ALB: Albumin; GLO: Globulin; A/G: Albumin/globulin; GGT: Gamma-glutamyltransferase; ALP: Alkaline phosphatase; AFP: Alpha-fetoprotein; CEA: Carcinoembryonic antigen; CA125: Carbohydrate antigen 125; ALBI: Albumin bilirubin.

Citation: Wang ZM, Pan SP, Zhang JJ, Zhou J. Prediction and analysis of albumin-bilirubin score combined with liver function index and carcinoembryonic antigen on liver metastasis of colorectal cancer. World J Gastrointest Surg 2024; 16(6): 1670-1680
URL: https://www.wjgnet.com/1948-9366/full/v16/i6/1670.htm
DOI: https://dx.doi.org/10.4240/wjgs.v16.i6.1670