Prediction and analysis of albumin-bilirubin score combined with liver function index and carcinoembryonic antigen on liver metastasis of colorectal cancer

doi:10.4240/wjgs.v16.i6.1670

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Surg. Jun 27, 2024; 16(6): 1670-1680
Published online Jun 27, 2024. doi: 10.4240/wjgs.v16.i6.1670

Table 1 Baseline data between liver metastasis group and non-liver metastasis group (n = 195)

Index	Liver metastases group (n = 70)	Non-liver metastases group (n = 125)	P value
Age (mean ± SD, yr)	58.3 ± 12.5	61.7 ± 12.0	0.067
Gender, n (%)			0.865
Man	40 (57.1)	73 (58.4)
Female	30 (42.9)	52 (41.6)
Primary tumor location, n (%)			0.042
Colon	38 (54.3)	49 (39.2)
Rectum	32 (45.7)	76 (60.8)
BMI, M (P₂₅, P₇₅), kg/m²	22.5 (21.4, 24.7)	22.1 (20.2, 25.0)	0.28
TBIL, M (P₂₅, P₇₅), μmol/L	14.9 (11.6, 24.7)	12.8 (9.4, 16.9)	0.001
DBIL, M (P₂₅, P₇₅), μmol/L	7.2 (4.3, 10.6)	3.3 (2.3, 5.4)	< 0.001
IBIL, M (P₂₅, P₇₅), μmol/L	9.3 (5.2, 14.3)	8.8 (6.0, 12.1)	0.642
ALT, M (P₂₅, P₇₅), U/L	31.5 (16.0, 54.8)	17.0 (10.0, 25.0)	< 0.001
AST, M (P₂₅, P₇₅), U/L	40.0 (27.8, 87.3)	20.0 (16.0, 25.5)	< 0.001
AST/ALT, M (P₂₅, P₇₅)	1.6 (1.1, 2.2)	1.4 (0.9, 1.7)	0.005
TP, M (P₂₅, P₇₅), g/L	65.1 (58.9, 70.6)	69.4 (64.3, 73.4)	0.001
ALB, M (P₂₅, P₇₅), g/L	36.3 (29.5, 40.2)	41.4 (38.3, 44.1)	< 0.001
GLO, M (P₂₅, P₇₅), g/L	29.3 (24.7, 33.5)	28.3 (24.0, 31.0)	0.124
A/G (mean ± SD)	1.2 ± 0.4	1.5 ± 0.3	< 0.001
GGT, M (P₂₅, P₇₅), U/L	59.0 (25.8, 148.0)	18.0 (13.0, 25.5)	< 0.001
ALP, M (P₂₅, P₇₅), U/L	122.5 (77.5, 211.0)	76.0 (63.0, 90.5)	< 0.001
AFP, M (P₂₅, P₇₅), μg/L	2.6 (1.6, 3.4)	2.5 (1.8, 3.2)	0.845
CEA, M (P₂₅, P₇₅), μg/L	79.5 (12.5, 476.0)	2.9 (1.8, 5.9)	< 0.001
CA125, M (P₂₅, P₇₅), U/mL	21.3 (11.0, 54.7)	11.1 (7.9, 16.7)	< 0.001
CA19-9, M (P₂₅, P₇₅), U/mL	85.5 (17.3, 801.7)	10.9 (7.5, 17.0)	< 0.001
ALBI score, M (P₂₅, P₇₅)	-2.3 (-2.7, -1.6)	-2.8 (-3.0, -2.6)	< 0.001

BMI: Body mass index; TBIL: Total bilirubin; DBIL: Direct bilirubin; IBIL: Indirect bilirubin; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; TP: Total protein; ALB: Albumin; GLO: Globulin; A/G: Albumin/globulin; GGT: Gamma-glutamyltransferase; ALP: Alkaline phosphatase; AFP: Alpha-fetoprotein; CEA: Carcinoembryonic antigen; CA125: Carbohydrate antigen 125; ALBI: Albumin bilirubin.

Citation: Wang ZM, Pan SP, Zhang JJ, Zhou J. Prediction and analysis of albumin-bilirubin score combined with liver function index and carcinoembryonic antigen on liver metastasis of colorectal cancer. World J Gastrointest Surg 2024; 16(6): 1670-1680
URL: https://www.wjgnet.com/1948-9366/full/v16/i6/1670.htm
DOI: https://dx.doi.org/10.4240/wjgs.v16.i6.1670