Clinical study of neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio in hypertriglyceridemia-induced acute pancreatitis and acute biliary pancreatitis with persistent organ failure

doi:10.4240/wjgs.v16.i6.1647

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 16, Issue 6

This Article

Academic Content and Language Evaluation of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (296)

All Articles published online

The chart showing PDF series, HTML series, Figures (1-2) series, Tables (1-5) series.

Item

Count

PDF

HTML

210

Figures (1-2)

Tables (1-5)

Sum=281

Publishing Process of This Article

The chart showing Browse series, Download series.

Item

Count

Browse

Download

Sum=6

Jun 27, 2024 (publication date) through Jul 17, 2024

Times Cited of This Article

Times Cited (0)

Journal Information of This Article

Publication Name

World Journal of Gastrointestinal Surgery

ISSN

1948-9366

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Study

World J Gastrointest Surg. Jun 27, 2024; 16(6): 1647-1659
Published online Jun 27, 2024. doi: 10.4240/wjgs.v16.i6.1647

Table 1 Baseline characteristics

Characteristics		Overall (771)	HTGP (241)	ABP (530)	P value
Age (yr)		49 (37.0; 63.0)	37 (26.0; 53.8)	56 (30.0; 84.0)	< 0.001
Sex, n (%)					< 0.001
	Male	466 (60.4)	184 (76.3)	282 (53.2)
	Female	305 (39.6)	57 (23.7)	248 (46.8)
BMI (kg/m²)		26 (23.4; 28.7)	27.8 (22.0; 35.3)	25.4 (19.0; 33.7)	< 0.001
Smoking, n (%)					< 0.001
	N	515 (66.8)	131 (54.4)	384 (72.5)
	Y	256 (33.2)	110 (45.6)	146 (27.5)
Drinking, n (%)					< 0.001
	N	550 (71.3)	147 (61)	403 (76)
	Y	221 (28.7)	94 (39)	127 (24)
Diabetes, n (%)					< 0.001
	N	643 (83.4)	173 (71.8)	470 (88.7)
	Y	128 (16.6)	68 (28.2)	60 (11.3)
Hypertension, n (%)					< 0.001
	N	581 (75.4)	202 (83.8)	379 (71.5)
	Y	190 (24.6)	39 (16.2)	151 (28.5)
Hyperlipidemia, n (%)					< 0.001
	N	583 (75.6)	88 (36.5)	495 (93.4)
	Y	188 (24.4)	153 (63.5)	35 (6.6)
Laboratory data
	ALT	63.6 (26.0; 181.3)	31.9 (9.7; 111.7)	108.8 (13; 616.8)	< 0.001
	AST	46.2 (24.4; 130.2)	28.8 (13.0; 114.1)	70.1 (16.1; 638.0)	< 0.001
	ALP	108.9 (79.1; 108.9)	101.1 (41.9; 118.1)	108.9 (55.3; 258.5)	< 0.001
	γ-GT	219.5 (119.7; 219.5)	219.5 (17.6; 318.2)	219.5 (31.0; 696.6)	< 0.001
	ALB	36.4 (31.8; 41.4)	37.0 (21.6; 48.6)	36.3 (18.3; 48.3)	0.018
	TBIL	23.7 (14.4; 36.7)	19.9 (3.0; 44.4)	27.1 (5.1; 106.1)	< 0.001
	DBIL	8.8 (3.8; 13.4)	4.0 (0.6; 15.1)	11.2 (2.5; 67.2)	< 0.001
	TC	4.8 (3.4; 5.4)	6.8 (3.3; 17.7)	4.0 (1.0; 5.5)	< 0.001
	TG	1.9 (0.9; 3.9)	7.4 (1.0; 38.8)	1.1 (0.3; 3.9)	< 0.001
	SCr	75.9 (62.9; 86.9)	79.0 (43.4; 157.4)	75.0 (48.4; 127.3)	0.174
	AMY	256.0 (82.6; 729.5)	191.6 (30.0; 927.5)	343.1 (38.4; 2053.5)	< 0.001
	LPS	344.3 (97.7; 878.8)	323.2 (47.5; 1312.0)	391.9 (28.4; 1709.6)	0.15
	PT-S	12.8 (11.9; 13.3)	12.2 (10.7; 14.4)	12.9 (11.1; 16.0)	< 0.001
	FIB	4.4 (3.3; 5.2)	5.2 (2.6; 9.0)	4.1 (2.4; 6.9)	< 0.001
	WBC	11.1 (7.7; 14.5)	11.8 (5.8; 21.0)	10.6 (4.6; 20.2)	< 0.001
	Lym	1.1 (0.7; 1.5)	1.3 (0.7; 3.1)	1.0 (0.4; 2.1)	< 0.001
	RBC	4.6 (4.1; 5.1)	5.0 (4.0; 6.1)	4.4 (3.4; 5.7)	< 0.001
	RDW	13.3 (12.5; 14.1)	13.2 (9.8; 14.4)	13.5 (9.9; 16.2)	0.003
	PLT	203.0 (164.0; 254.0)	223.0 (134.1; 391.0)	197.0 (103.6; 339.4)	< 0.001
	PDW	16.8 (16.3; 17.4)	17.3 (12.8; 19.1)	16.6 (11.8; 18.1)	< 0.001
NLR		8.3 (4.5; 14.2)	6.9 (1.6; 18.9)	9.1 (2.1; 33.1)	< 0.001
PLR		184.3 (131.6; 273.6)	160.5 (70.3; 379.0)	203.1 (83.4; 518.6)	< 0.001
Atlanta classification, n (%)					0.001
	MAP	437 (56.7)	125 (51.9)	312 (58.9)
	MSAP	156 (20.2)	40 (16.6)	116 (21.9)
	SAP	178 (23.1)	76 (31.5)	102 (19.2)
Scoring systems
	MCTSI	4.0 (2.0; 6.0)	4.0 (2.0; 8.0)	4.0 (2.0; 8.0)	0.005
	JSS	1.0 (0; 2.0)	1.0 (0; 4.0)	1.0 (0; 4.0)	0.029
	BISAP	1.0 (0; 1.0)	0 (0; 2.0)	1.0 (0; 2.0)	< 0.001
	Modified Marshall	2.0 (1.0; 4.0)	2.0(0; 5.9)	2.0 (0; 7.0)	0.049
	SOFA	1.0 (0; 3.0)	1.0 (0; 4.0)	1.0 (0; 5.0)	0.163
POF, n (%)					0.247
	N	537 (69.6)	161 (66.8)	376 (70.9)
	Y	234 (30.4)	80 (33.2)	154 (29.1)
SIRS, n (%)					0.956
	N	465 (60.3)	145 (60.2)	320 (60.4)
	Y	306 (39.7)	96 (39.8)	210 (39.6)
Hospital stay (d)		13.5 (9.4; 19.2)	12.0 (5.2; 29.3)	14.3 (5.4; 36.1)	< 0.001
Mortality, n (%)					0.556
	N	762 (98.8)	239 (99.2)	523 (98.7)
	Y	9 (1.2)	2 (0.8)	7 (1.3)

N: No; Y: Yes; BMI: Body mass index; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; ALP: Alkaline phosphatase; γ-GT: Gamma-glutamyl transferase; ALB: Albumin; TBIL: Total bilirubin; DBIL: Direct bilirubin; TC: Total cholesterol; TG: Triglycerides; SCr: Serum creatinine; AMY: Serum amylase; LPS: Lipase; PT-S: Prothrombin time; FIB: Fibrinogen; WBC: White blood cell; Lym: Lymphocyte; RBC: Red blood cell; RDW: Red blood cell distribution width; PLT: Platelet; PDW: Platelet distribution width; MCTSI: Modified computed tomography severity index score; JSS: Japanese Severity Score; BISAP: Bedside Index of Severity in Acute Pancreatitis; Modified Marshall: Modified Organ Dysfunction Score; SOFA: Sequential Organ Failure Assessment Score; SIRS: Systemic Inflammatory Response Syndrome; NLR: Neutrophil-to-lymphocyte ratio; PLR: Platelet-to-lymphocyte ratio; HTGP: Hypertriglyceridemia-induced acute pancreatitis; ABP: Acute biliary pancreatitis.

Citation: Xu MS, Xu JL, Gao X, Mo SJ, Xing JY, Liu JH, Tian YZ, Fu XF. Clinical study of neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio in hypertriglyceridemia-induced acute pancreatitis and acute biliary pancreatitis with persistent organ failure. World J Gastrointest Surg 2024; 16(6): 1647-1659
URL: https://www.wjgnet.com/1948-9366/full/v16/i6/1647.htm
DOI: https://dx.doi.org/10.4240/wjgs.v16.i6.1647