Optimal extent of lymphadenectomy improves prognosis and guides adjuvant chemotherapy in esophageal cancer: A propensity score-matched analysis

Table 3 Multivariate analysis for overall survival

Prognostic factors		P value	HR (95%CI)
Maximal tumor diameter		0.667	1 (0.99-1.01)
T (ref T1)
	T2	0.055	2.04 (0.99-4.20)
	T3	0.002	3.09 (1.51-6.31)
	T4	0.005	7.44 (1.82-30.35)
N (ref N0)
	N1	0.077	1.35 (0.97-1.89)
	N2	0.075	1.46 (0.96-2.21)
	M3	0.002	1.99 (1.28-3.11)
G (ref G1)
	G2	0.103	1.42 (0.93-2.16)
	G3	0.387	1.25 (0.76-2.05)
Venous thrombus (ref negative)	Positive	< 0.001	1.8 (1.34-2.42)
Perineurial invasion (ref negative)	Positive	0.088	1.29 (0.96-1.71)
Adjuvant chemotherapy (ref no)	Yes	0.738	0.95 (0.71-1.27)
NRLN (ref ≤ 21)	> 21	0.004	0.66 (0.50-0.87)

NRLN: Number of removed lymph nodes; HR: Hazards regression; CI: Confidence interval.