Should we perform decompressive laparotomy during severe acute pancreatitis with intra-abdominal hypertension below 25 mmHg: Only the gut knows

Table 1 Patients characteristics

Characteristics	Population	Ischemia	No ischemia
	n = 18	n = 6	n = 12
Baseline characteristics
Age (yr)	60 [43; 67]	59 [54; 60]	60 [39; 70]
Male sex	16/18 (89%)	5/6 (83%)	11/12 (92%)
BMI (kg/m2)	31.7 [29.8; 35.7]	35.3 [32.2; 37.2]	30.6 [29.3; 32.1]
CTSI score	6 [4; 8]	7 [6; 9]	6 [4; 8]
SOFA score at ICU admission	7 [4; 11]	8 [6; 13]	7 [4; 10]
Severity at the time of laparotomy
IAP (mmHg)	20 [17; 24]	20 [18; 22]	21 [18; 25]
pH	7.26 [7.07; 7.30]	7.06 [6.93; 7.24]	7.27 [7.19; 7.32]
Lactate (mmol/L)	3.6 [2.9; 7.4]	10.4 [4.4; 15.0]	3.3 [2.8; 3.8]
SOFA	10 [9; 12]	14 [12; 17]	9 [8; 11]
PaO2/FIO2	174 [108; 227]	122 [108; 174]	206 [106; 258]
Norepinephrine dose (µg/kg/min)	0.71 [0.42; 0.88]	1.04 [0.50; 1.39]	0,63 [0.45; 0.72]
Non occlusive mesenteric ischemia
Transmural necrosis	6/18 (33%)	6	0
NOMI location
Localised-colon		2/6
Diffuse- Ileum/jejunum + colon		4/6
Surgical resection		4/6
Surgical abstention for futility		2/6
Outcome
28-d mortality	6/18 (33%)	4/6 (66%)	2/12 (17%)
1-yr mortality	10/18 (56%)	4/6 (66%)	6/12 (50%)
ICU length of stay (d)	24 [8; 45]	5 [2; 11]	44 [20; 67]
Hospital length of stay (d)	40 [10; 58]	6 [3; 29]	51 [30; 116]

Data are median [IQR] or n (%). BMI: Body mass index; CTSI: Computed tomography severity score; SOFA: Sequential organ failure assessment; IAP: Intra-abdominal pressure; NOMI: Non occlusive mesenteric ischemia; ICU: Intensive care unit.