GLI1 and PTTG1 expression in colorectal carcinoma patients undergoing radical surgery and their correlation with lymph node metastasis

Table 2 Correlation of GLI1 expression with clinicopathological data of patients undergoing radical surgery for colorectal carcinoma

Grouping	n	GLI1 positive (n = 65), n (%)	GLI1 negative (n = 38), n (%)	χ2	P value
Sex				0.403	0.526
Male	53	35 (53.85)	18 (47.37)
Female	50	30 (46.15)	20 (52.63)
Age				3.504	0.061
< 60 yr old	42	22 (33.85)	20 (53.63)
≥ 60 yr old	61	43 (66.15)	18 (47.37)
Tumor location				0.221	0.638
Colon	43	26 (40.00)	17 (44.74)
Rectum	60	39 (60.00)	21 (55.26)
Differentiation degree				0.552	0.458
High differentiation	23	13 (20.00)	10 (26.32)
Medium–low differentiation	80	52 (80.00)	28 (73.68)
Pathological staging				3.086	0.079
I–II	48	26 (40.00)	22 (57.89)
III–IV	55	39 (60.00)	16 (42.11)
Lymph node metastasis				5.233	0.022
Positive	58	44 (67.69)	17 (44.74)
Negative	45	21 (32.31)	21 (55.26)