Clinical characteristics and risk factors of post-operative intestinal flora disorder following laparoscopic colonic surgery: A propensity-score-matching analysis

Table 3 Uni-variate analysis after propensity score matching

Factors	IFD (n = 97)	Non-IFD (n = 194)	χ²	OR (95%CI)	P value
Age (< 65/≥ 65 yr)	57/40	110/84	0.112	1.09 (0.66-1.78)	0.737
BMI (< 24/≥ 24 kg/m2)	51/46	105/89	0.062	0.94 (0.58-1.53)	0.803
The systom of obstruction (No/Yes)	70/27	153/41	1.622	0.69 (0.40-1.22)	0.203
Total colonscopy (No/Yes)	43/54	73/121	1.211	1.32 (0.80-2.16)	0.271
The CFR occupation (≥ 1/2/< 1/2)	63/34	131/63	0.193	0.89 (0.53-1.49)	0.660
Neoadjuvant therapy (No/Yes)	91/6	181/11	0.031	0.91 (0.33-2.54)	0.860
Colonscopy pre-surgery (No/Yes)	71/26	151/43	0.769	0.78 (0.44-1.37)	0.380
Re-location pre-surgery (No/Yes)	76/21	166/28	2.405	0.61 (0.33-1.14)	0.121
Polypectomy pre-surgery (No/Yes)	83/14	172/22	0.571	0.76 (0.37-1.56)	0.450
Obstruction pre-surgery (No/Yes)	83/14	185/9	8.521	0.29 (0.12-0.69)	0.004
PGEP (1-2/3 packages)	63/34	139/55	1.368	1.36 (0.81-2.30)	0.243
Cephingosporins pre-surgery (No/Yes)	87/10	159/35	2.957	1.92 (0.90-4.05)	0.085
Metronidazole pre-surgery (No/Yes)	49/48	134/60	9.541	0.46 (0.28-0.75)	0.002
Operation duration (≥ 130/< 130 min)	48/49	102/92	0.248	0.88 (0.54-1.44)	0.619
Total blood loss (≥ 20/< 20 mL)	66/31	138/56	0.295	0.86 (0.51-1.46)	0.587
Stoma (No/Yes)	93/4	192/2	1.723	0.24 (0.04-1.35)	0.189
Antibotics post-surgery (No/Yes)	79/18	187/7	18.401	0.16 (0.07-0.41)	< 0.001
Nutrition supply pre-surgery, n (%)			33.880		< 0.001
EN	42 (43.3)	37 (19.1)		1 (Refrence)
PN	17 (17.5)	99 (51.0)		6.61(3.35-13.03)
GNS	38 (39.2)	58 (29.9)		1.73 (0.95-3.16)

IFD: Intestinal flora disorder; BMI: Body mass index; CFR: Circumferential range; PGEP: Polyethylene glycol electrolytes powder; EN: Enteral nutrition; PN: Parenteral nutrition; GNS: Glucose and sodium chloride injection.