Suspected coexistence of perianal necrotizing sweet syndrome in chronic myelomonocytic leukemia: A case report

Table 2 Major and minor criteria for Sweet’s syndrome

Major	(1) Abrupt onset of tender or painful erythematous plaques or nodules occasionally with vesicles, pustules or bullae
	(2) Predominantly neutrophilic infiltration in the dermis without leukocytoclastic vasculitis
Minor	(1) Preceded by a nonspecific respiratory or gastrointestinal tract infection or vaccination or associated with:
	Inflammatory diseases such as chronic autoimmune disorders, infections
	Hemoproliferative disorders or solid malignant tumors
	Pregnancy
	(2) Accompanied by periods of general malaise and fever (> 38 °C)
	(3) Laboratory values during onset: ESR > 20 mm; C-reactive protein positive; segmented-nuclear neutrophils and stabs > 70% in peripheral blood smear; leukocytosis > 8000 (three of four of these values necessary)
	(4) Excellent response to treatment with systemic corticosteroids or potassium iodide

Both major and two minor criteria are needed for diagnosis. ESR: Erythrocyte sedimentation rate.