Inflammatory responses in esophageal mucosa before and after laparoscopic antireflux surgery

Table 2 Cell signaling proteins

Protein	mean ± SD (FI)	Median	Variance
MEK1
Post-LARS	344.9 ± 328.5	288.5a	102992.8
Pre-LARS	416.3 ± 697.9	230	464957.9
HC	161.9 ± 151.4	102.5	22920.5
c-Jun
Post-LARS	48.9 ± 17.4a	49	287.8
Pre-LARS	43.8 ± 10.9	42	113.6
HC	50.9 ± 11	50.5	121.1
p38-MAPK
Post-LARS	16.3 ± 15.2	10.0a	219.9
Pre-LARS	12.1 ± 10.5	8	106
HC	7.3 ± 1.2	7	1.3
NF-κB
Post-LARS	10.5 ± 1.9a,b	10.5	3.4
Pre-LARS	8.8 ± 3	8	8.4
HC	8.2 ± 1.6	8.5	2.6

^aP < 0.05 vs healthy control.

^bP < 0.05 vs pre-laparoscopic anti-reflux surgery.

mean ± SD values are given for Student’s t test, Median and Variance values are given for Mann-Whitney U test. LARS: Laparoscopic anti-reflux surgery; HC: Healthy control; NF-κB: Nuclear factor kappa-beta.