Pre-operative visceral adipose tissue radiodensity is a potentially novel prognostic biomarker for early endoscopic post-operative recurrence in Crohn’s disease

Table 2 Multivariate regression of radiographic mesenteric parameters associated with early endoscopic post-operative recurrence and severity of endoscopic post-operative recurrence

	Early endoscopic POR	Severity of endoscopic POR
	aOR (95%CI)	aOR (95%CI)
VAT volume (cm3)	1.23 (0.78-1.95)	1.08 (0.72-1.53)
VAT:SAT volume	0.80 (0.53-1.20)	0.80 (0.56-1.14)
VAT Radiodensity (HU)	0.59 (0.38-0.90)	0.60 (0.42-0.87)
VAT:SAT Radiodensity	8.54 (1.48-49.28)	6.26 (1.43-27.42)
Severe vasa recta engorgement	1.53 (0.64-3.66)	1.61 (0.75-3.46)
Mesenteric lymphadenopathy	1.59 (0.67-3.79)	2.10 (0.99-4.47)

Adjusted age at surgery, sex, time from Crohn’s disease (CD) diagnosis to surgery, internal penetrating disease behavior, post-operative prophylaxis status, and prior CD-related surgery. VAT: Visceral adipose t issue; SAT: Subcutaneous adipose tissue; POR: Post-operative recurrence; HU: Hounsfield units; aOR: Adjusted odds ratios; CI: Confidence interval.