Influence of donor age on liver transplantation outcomes: A multivariate analysis and comparative study

Table 6 Cox proportional hazards model-excluded metrics (Model for End-Stage Liver Disease, Balance of Risk, and Eurotransplant Donor Risk Index score) and retransplanted patients

Variable	Coefficient (95%CI)	Hazard ratio (95%CI)	P value
Donor pre-procurement cardiac arrest (yes)	0.406 (-0.006, 0.817)	1.500 (0.994, 2.264)	0.053
Recipient age	0.035 (0.016, 0.055)	1.035 (1.016, 1.004)	< 0.001
Donor CRP	0.002 (0.000, 0.004)	1.002 (1.000, 1.004)	0.015
Indication for LT-cancer (HCC, CCC)	0.064 (-0.341, 0.469)	1.066 (0.711, 1.599)	0.757
Indication for LT-hepatitis C virus	1.058 (0.538, 1.578)	2.881 (1.712, 4.846)	< 0.001
Indication for LT-miscellaneous	0.365 (-0.128, 0.859)	1.442 (0.880, 2.361)	0.146
Indication for LT-cholestatic disease	-0.328 (-1.126, 0.470)	0.720 (0.324, 1.600)	0.420

The final model did not include any transformations and interactions, as they were insignificant, and the final model is the (linear) main effects model. CRP: C-reactive protein; LT: Liver transplantation; HCC: Hepatocellular carcinoma; CCC: Cholangiocarcinoma.