Value of serum pepsinogen ratio screening for early gastric cancer and precancerous lesions in Youcheng area

Table 3 Value of pepsinogen ratio screening for early gastric cancer

Screening indicator	Indicators	AUC	SE	95%CI	Cut-off value	Specificity (%)	Sensitivity (%)
Precancerous lesions and early GC	PGR	0.618	0.036	0.547-0.690	20.48	36.59	99.21
	H. pylori	0.502	0.037	0.430-0.573	/	59.35	40.94
	Combined detection	0.618	0.036	0.547-0.689	0.39	98.43	36.59
Benign lesions and early GC	PGR	0.708	0.032	0.644-0.771	20.68	50.37	99.21
	H. pylori	0.581	0.035	0.511-0.650	/	57.04	59.06
	Combined detection	0.750	0.030	0.690-0.809	0.38	44.44	99.21

GC: Gastric cancer; PGR: Pepsinogen ratio; AUC: Area under the curve; H. pylori: Helicobacter pylori; CI: Confidence interval.