Massive simultaneous hepatic and renal perivascular epithelioid cell tumor benefitted from surgery and everolimus treatment: A case report

Figure 6 Pathological findings of surgical specimens. A and B: The histopathological examination of surgical specimens from liver and kidney lesions showed tumor lesions mainly composed of dysplasia epithelioid cells with rich and red-stained cytoplasm and large, atypical and vacuolated nuclei, and prominent nucleolus (hematoxylin-eosin, original magnification × 100 and × 400); C and D: The surgical specimens from the liver and kidney lesions showed strong and diffuse granular cytoplasmic immunoreactivity for HMB-45 in epithelioid tumor cells (original magnification × 100 and × 400); E and F: The surgical specimens from the liver and kidney lesions exhibited intense and partly cytoplasmic expression of melan-A, with a staining pattern similar to that of HMB-45 (original magnification × 100 and × 400); G and H: The surgical specimens from the liver and kidney lesions revealed weak and punctate nuclear immunoreactivity for TFE3 in the epithelioid tumor cells (original magnification × 100 and × 400); I and J: The surgical specimens from the liver and kidney lesions displayed weak expression of Ki67 in the nuclei of the epithelioid cells (original magnification × 100).