Postoperative serum tumor markers-based nomogram predicting early recurrence for patients undergoing radical resections of pancreatic ductal adenocarcinoma

Figure 4 Stratified analysis of recurrence free survival by independent risk factors of early recurrence. A: Kaplan-Meier survival analysis of recurrence free survival (RFS) stratified by perineural invasion. Patients with perineural invasion of their tumors had poorer RFS than those without; B: Kaplan-Meier survival analysis of RFS stratified by pathological stage. Patients with stage III tumor had poorer RFS than those without; C: Kaplan-Meier survival analysis of RFS stratified by preoperative serum carbohydrate antigen 125 (CA125). Patients with Pre_CA125 > 13.80 U/mL had poorer RFS than those with Pre_CA125 ≤ 13.80 U/mL; D: Kaplan-Meier survival analysis of RFS stratified by postoperative serum carbohydrate antigen 19-9 (CA19-9). Patients with Af_CA19-9 > 34.42 U/mL had poorer RFS than those with Af_CA19-9 ≤ 34.42 U/mL; E: Kaplan-Meier survival analysis of RFS stratified by postoperative serum carcinoembryonic antigen (CEA). Patients with Af_CEA > 2.93 ng/mL had poorer RFS than those with Af_CEA ≤ 2.93 ng/mL. CA125: Carbohydrate antigen 125; CA19-9: Carbohydrate antigen 19-9; CEA: Carcinoembryonic antigen; RFS: Recurrence free survival.