Recurrence scoring system predicting early recurrence for patients with pancreatic ductal adenocarcinoma undergoing pancreatectomy and portomesenteric vein resection

Figure 2 Receiver operating characteristics curve and survival analyses of serum recurrence score in the training cohort. A: Receiver operating characteristics (ROC) curves of serum recurrence score (SRS) and top six (AUC) serum-derived variables for predicting early recurrence (ER). The AUC of SRS was superior to the AUCs of other serum-derived variables; B: Time-dependent ROC curve of SRS for predicting recurrence, the AUCs of SRS varied over time (months); C: Stacked plot showing significantly different ratios of ER and delayed recurrence, in the high-SRS (SRS > 0.53) and low-SRS (SRS ≤ 0.53) groups, respectively (P value = 2.719e-09); D and E: Kaplan-Meier survival analysis for patients with high SRS and low SRS. The high-SRS group showed significantly poorer recurrence free survival and overall survival compared with the low-SRS group. SRS: Serum recurrence score; ROC: Receiver operating characteristics; AUC: Area under the curve; ER: Early recurrence.