Recurrence scoring system predicting early recurrence for patients with pancreatic ductal adenocarcinoma undergoing pancreatectomy and portomesenteric vein resection

Figure 1 Construction of serum recurrence score based on perioperative serum-derived variables. A: Univariate Cox regression analysis and Forest plot of perioperative serum-derived variables; B: LASSO regression analysis of 15 serum-derived variables (P value < 0.1) and shrinkage coefficient diagram. Y-axis represents coefficients of variables, and X-axis represents the penalty coefficient (Lambda). As the log Lambda increases, more coefficients of variables will decrease to zero; C: Cross validation (5-fold) of LASSO regression analysis. Dotted vertical line indicates the minimum and one standard error of Lambda values. The one standard error value of Lambda was used as the penalty coefficient. CA: Carbohydrate antigen; CEA: Carcinoembryonic antigen; ALB: Albumin; NLR: Neutrophils, lymphocytes ratio; PLR: Platelets to lymphocytes ratio; LMR: Lymphocytes to monocytes ratio; NAR: Neutrophil to albumin ratio; PAR: Platelet to albumin ratio.