Relationship between intracranial pressure and neurocognitive function among older adults after radical resection of rectal cancer

Table 3 Comparison of h1, h2, h3, h4, mean arterial pressure, heart rate and end-tidal carbon dioxide partial pressure between the two groups

	Timepoints/ANOVA factors	Group A1	Group A2	F value	P value
MAP	Before anesthesia	75.60 ± 2.33	76.40 ± 1.93	3.68	0.058
	30 minutes after the Trendelenburg position	90.19 ± 1.55	77.11 ± 1.28	2212.42	< 0.001
	60 minutes after the Trendelenburg position	91.62 ± 1.34	78.41 ± 1.55	2028.42	< 0.001
	After extubation	78.74 ± 1.11	78.59 ± 0.93	0.571	0.452
	Time effect			703.67a	0.024a
	Group effect			993.59a	0.014a
	Interaction effect			535.37a	0.033a
HR	Before anesthesia	81.95 ± 2.24	82.40 ± 1.62	1.39	0.241
	30 minutes after the Trendelenburg position	75.26 ± 1.62	75.81 ± 1.96	2.251	0.137
	60 minutes after the Trendelenburg position	73.79 ± 2.07	74.70 ± 2.54	3.752	0.055
	After extubation	85.14 ± 1.76	85.79 ± 2.35	2.342	0.129
	Time effect			592.05	0.015
	Group effect			7.59	0.011
	Interaction effect			0.07	0.981
PETCO2	Before anesthesia	31.07 ± 1.09	30.70 ± 1.35	2.229	0.139
	30 minutes after the Trendelenburg position	41.05 ± 1.06	40.76 ± 1.19	1.589	0.211
	60 minutes after the Trendelenburg position	42.38 ± 0.49	41.97 ± 1.78	2.148	0.146
	After extubation	34.43 ± 1.35	34.24 ± 1.47	0.453	0.502
	Time effect			1553.13	0.004
	Group effect			4.61	0.041
	Interaction effect			0.16	0.921

^aP value of Mauchly’s spherical test is less than 0.05, and the F value or P value has been corrected by Greenhouse-Geisser. The P value of the group effect of the above indicators is less than 0.05, indicating that the group A1 and A2 have statistically significant differences in the effects of mean arterial pressure, heart rate and end-tidal carbon dioxide partial pressure.

MAP: Mean arterial pressure; HR: Heart rate; PETCO₂: End-tidal carbon dioxide partial pressure.